I was wondering the same thing. It doesn't appear as though they're keeping a lot of the more religious mythology aspects based on that trailer. I mean... maybe they're going to surprise the non-comic audience with it, but still... I think we saw Herr Starr, and a glance of Tulip, and maybe Cassidy in the jail cell? But umm... what about Genesis? Pretty sure swerving the audience with angels/demons/Genesis/etc might not really be the best way to gain audience.
I like the chances of the series being successful if they don't show the religious parts of the comic. They can still have a good plot without it.
Uh...what? The 'religious parts' are the core of the story. Angel/Devil offspring. Search for God. Destroying Angel seeking vengeance. If it doesn't have these elements, what's the point? Why call it 'Preacher'? Does anyone know how much Garth Ennis has to do with the production/writing? Hopefully he has a key role such as Kirkman's on TWD.
Said it better then I ever could.