Here are my options for my collection:
1) Pass it along. If my son (or future son/daughter) wants them, the comics go to them.
2) If my son and future children decline, I will work to sell the collection. I will probably determine all of this by the time I am 60 or so, giving me enough time to sell off my collection. The money will likely be used partially for myself and my wife, the rest to my children. Perhaps we all take a nice family vacation or something together and then the rest of the money goes to the children.
As for stuff that does not sell, I have always thought of mailing out random comics to people who need them. Basically, they cover postage, the book (or books) are theirs. In this way, everything truly finds a good home. This or donating to a school or someplace where they can be enjoyed by the original people they were meant for, kids.