I started off like you, trying to get a near complete collection with all the editions and variants, then when I saw how many variants there was for the reboot of ASM, I decided to just get the regular covers of every issue. Then, I decided to just stop at 700 because of all the reboots Marvel had started. Then the recent clone conspiracy storyline reminded me of the dumb sins past storyline and decided to stop at 500 instead, to avoid that. And now, I just stopped trying to complete a run to 500 because I wanted to downsize from having so many boxes. So if you head down this route that I took, it actually feels like a big relief trying not to get everything ASM.
I don't know if this is Marvel's intention, but it helped me save more money
I made it from ASM 201 to 700 with quite a few variants that I thought mattered. Then when ASM volume 3 started I tried to collect all of those variants but then I noticed that they just keep rebooting ASM back to "number one". To be honest that's when I said screw it and decided to focus on finishing up my early ASM issues with high grades.